English Intern
    Muskuloskelettales Centrum Würzburg

    Originalarbeiten

    Originalarbeiten 2017
    • Solimando AG, Brandl A, Mattenheimer K, Graf C, Ritz M, Ruckdeschel A, StühmerT, Mokhtari Z, Rudelius M, Dotterweich J, Bittrich M, Desantis V, Ebert R,Trerotoli P, Frassanito MA, Rosenwald A, Vacca A, Einsele H, Jakob F, Beilhack A.JAM-A as a prognostic factor and new therapeutic target in multiple myeloma.Leukemia. 2017 Sep 28. doi: 10.1038/leu.2017.287. [Epub ahead of print]
    • Bertlein S, Brown G, Lim KS, Jungst T, Boeck T, Blunk T, Tessmar J, Hooper GJ,Woodfield TBF, Groll J. Thiol-Ene Clickable Gelatin: A Platform Bioink forMultiple 3D Biofabrication Technologies. Adv Mater. 2017 Oct 17. doi:10.1002/adma.201703404. [Epub ahead of print]
    • Huang G, Drakopoulos A, Saedtler M, Zou H, Meinel L, Heilmann J, Decker M.Cytotoxic properties of the alkaloid rutaecarpine and its oligocyclic derivativesand chemical modifications to enhance water-solubility. Bioorg Med Chem Lett.2017 Nov 1;27(21):4937-4941. doi: 10.1016/j.bmcl.2017.08.045. Epub 2017 Aug 24.
    • Hartmann S, Zwick L, Scheurer MJJ, Fuchs AR, Brands RC, Seher A, Böhm H,Kübler AC, Müller-Richter UDA. MAGE-A11 expression contributes to cisplatinresistance in head and neck cancer. Clin Oral Investig. 2017 Oct 15. doi:10.1007/s00784-017-2242-8. [Epub ahead of print]
    • Lagler C, El-Mesery M, Kübler AC, Müller-Richter UDA, Stühmer T, Nickel J,Müller TD, Wajant H, Seher A. The anti-myeloma activity of bone morphogeneticprotein 2 predominantly relies on the induction of growth arrest and isapoptosis-independent. PLoS One. 2017 Oct 13;12(10):e0185720. doi:10.1371/journal.pone.0185720. eCollection 2017.
    • Paxton NC, Smolan W, Böck T, Melchels FPW, Groll J, Juengst T. Proposal toAssess Printability of Bioinks for Extrusion-Based Bioprinting and Evaluation of Rheological Properties Governing Bioprintability. Biofabrication. 2017 Sep 20.doi: 10.1088/1758-5090/aa8dd8. [Epub ahead of print]
    • Stichler S, Böck T, Paxton NC, Bertlein S, Levato R, Schill V, Smolan W, MaldaJ, Tessmar J, Blunk T, Groll J. Double printing of hyaluronic acid /poly(glycidol) hybrid hydrogels with poly(ε-caprolactone) for MSC chondrogenesis.Biofabrication. 2017 Sep 14. doi: 10.1088/1758-5090/aa8cb7. [Epub ahead of print]
    • Radakovic D, Reboredo J, Helm M, Weigel T, Schürlein S, Kupczyk E, Leyh RG,Walles H, Hansmann J. A multilayered electrospun graft as vascular access forhemodialysis. PLoS One. 2017 Oct 12;12(10):e0185916. doi:10.1371/journal.pone.0185916. eCollection 2017.
    • Straßer M, Schrauth JHX, Dembski S, Haddad D, Ahrens B, Schweizer S, Christ B,Cubukova A, Metzger M, Walles H, Jakob PM, Sextl G. Calcium fluoride basedmultifunctional nanoparticles for multimodal imaging. Beilstein J Nanotechnol.2017 Jul 18;8:1484-1493. doi: 10.3762/bjnano.8.148. eCollection 2017.
    • Fernandez-Rebollo E, Eipel M, Seefried L, Hoffmann P, Strathmann K, Jakob F,Wagner W. Primary osteoporosis is not reflected by disease-specific DNAmethylation or accelerated epigenetic age in blood. J Bone Miner Res. 2017 Sep19. doi: 10.1002/jbmr.3298. [Epub ahead of print]
    • Holzapfel NP, Shokoohmand A, Wagner F, Landgraf M, Champ S, Holzapfel BM,Clements JA, Hutmacher DW, Loessner D. Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load. Am J Cancer Res. 2017 Jun 1;7(6):1322-1336.eCollection 2017.
    • Martine LC, Holzapfel BM, McGovern JA, Wagner F, Quent VM, Hesami P, WunnerFM, Vaquette C, De-Juan-Pardo EM, Brown TD, Nowlan B, Wu DJ, Hutmacher CO, Moi D,Oussenko T, Piccinini E, Zandstra PW, Mazzieri R, Lévesque JP, Dalton PD,Taubenberger AV, Hutmacher DW. Engineering a humanized bone organ model in miceto study bone metastases. Nat Protoc. 2017 Apr;12(4):639-663. doi:10.1038/nprot.2017.002. Epub 2017 Mar 2.
    • Schamel M, Barralet JE, Gelinsky M, Groll J, Gbureck U. Intrinsic 3DPrestressing: A New Route for Increasing Strength and Improving Toughness ofHybrid Inorganic Biocements. Adv Mater. 2017 Jul 17. doi: 10.1002/adma.201701035.[Epub ahead of print]
    • Burghartz M, Lennartz S, Schweinlin M, Hagen R, Kleinsasser N, Hackenberg S,Steußloff G, Scherzad A, Radeloff K, Ginzkey C, Walles H, Metzger M. Development of Human Salivary Gland-Like Tissue In Vitro. Tissue Eng Part A. 2017 Aug 4. doi:10.1089/ten.tea.2016.0466. [Epub ahead of print]
    • Ritzer J, Lühmann T, Rode C, Pein-Hackelbusch M, Immohr I, Schedler U, Thiele T, Stübinger S, Rechenberg BV, Waser-Althaus J, Schlottig F, Merli M, Dawe H,Karpíšek M, Wyrwa R, Schnabelrauch M, Meinel L. Diagnosing peri-implant diseaseusing the tongue as a 24/7 detector. Nat Commun. 2017 Aug 15;8(1):264. doi:10.1038/s41467-017-00340-x.
    • Lübtow MM, Hahn L, Haider MS, Luxenhofer R. Drug Specificity, Synergy andAntagonism in Ultrahigh Capacity Poly(2-oxazoline)/Poly(2-oxazine) basedFormulations. J Am Chem Soc. 2017 Aug 16;139(32):10980-10983. doi:10.1021/jacs.7b05376. Epub 2017 Aug 8.
    • Müller-Richter UDA, Gesierich A, Kübler AC, Hartmann S, Brands RC. Merkel CellCarcinoma of the Head and Neck: Recommendations for Diagnostics and Treatment.Ann Surg Oncol. 2017 Jul 31. doi: 10.1245/s10434-017-5993-1. [Epub ahead ofprint] Review.
    • Brands RC, Knierim LM, De Donno F, Steinacker V, Hartmann S, Seher A, KüblerAC, Müller-Richter UDA. Targeting VEGFR and FGFR in head and neck squamous cellcarcinoma in vitro. Oncol Rep. 2017 Sep;38(3):1877-1885. doi:10.3892/or.2017.5801. Epub 2017 Jul 10.
    • Ramani-Mohan RK, Schwedhelm I, Finne-Wistrand A, Krug M, Schwarz T, Jakob F, Walles H, Hansmann J. Deformation strain is the main physical driver for skeletal precursors to undergo osteogenesis in earlier stages of osteogenic cell maturation. J Tissue Eng Regen Med. 2017 Sep 5. doi: 10.1002/term.2565. [Epub ahead of print]
    • Müller-Deubert S, Seefried L, Krug M, Jakob F, Ebert R. Epidermal growth factor as a mechanosensitizer in human bone marrow stromal cells. Stem Cell Res.  2017 Aug 18;24:69-76. doi: 10.1016/j.scr.2017.08.012. [Epub ahead of print]
    • Horas K, Maier G, Jakob F, Maus U, Kurth A, Jakuscheit A, Rudert M, Holzapfel BM. High Prevalence of Vitamin D Deficiency in Patients with Bone Tumors. Cancer Invest. 2017 Aug 11:1-7. doi: 10.1080/07357907.2017.1351985. [Epub ahead of print]
    • Kishnani PS, Rush ET, Arundel P, Bishop N, Dahir K, Fraser W, Harmatz P,Linglart A, Munns CF, Nunes ME, Saal HM, Seefried L, Ozono K. Monitoring guidancefor patients with hypophosphatasia treated with asfotase alfa. Mol Genet Metab.2017 Jul 25. pii: S1096-7192(16)30374-2. doi: 10.1016/j.ymgme.2017.07.010. [Epub ahead of print] Review.
    • Shafiee A, Baldwin JG, Patel J, Holzapfel BM, Fisk NM, Khosrotehrani K,Hutmacher DW. Fetal bone marrow-derived mesenchymal stem/stromal cells enhancehumanization and bone formation of BMP7 loaded scaffolds. Biotechnol J. 2017 Sep 1. doi: 10.1002/biot.201700414. [Epub ahead of print]
    • Lorson T, Jaksch S, Lübtow MM, Jüngst T, Groll J, Lühmann T, Luxenhofer R. A Thermogelling Supramolecular Hydrogel with Sponge-Like Morphology as a Cytocompatible Bioink. Biomacromolecules. 2017 Jul 10;18(7):2161-2171. doi: 10.1021/acs.biomac.7b00481. Epub 2017 Jun 27.
    • Reuter C, Walles H, Groeber F. Preparation of a Three-Dimensional Full Thickness Skin Equivalent. Methods Mol Biol. 2017;1612:191-198. doi: 10.1007/978-1-4939-7021-6_14.
    • Fernandez-Rebollo E, Mentrup B, Ebert R, Franzen J, Abagnale G, Sieben T, Ostrowska A, Hoffmann P, Roux PF, Rath B, Goodhardt M, Lemaitre JM, Bischof O, Jakob F, Wagner W. Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells. Sci Rep. 2017 Jul 11;7(1):5132. doi: 10.1038/s41598-017-05207-1.
    • Castilho M, Feyen D, Flandes-Iparraguirre M, Hochleitner G, Groll J, Doevendans PAF, Vermonden T, Ito K, Sluijter JPG, Malda J. Melt Electrospinning Writing of Poly-Hydroxymethylglycolide-co-ε-Caprolactone-Based Scaffolds for Cardiac Tissue Engineering. Adv Healthc Mater. 2017 Jul 12. doi: 10.1002/adhm.201700311. [Epub ahead of print]
    • Henß A, Schamel M, Gbureck U, Gelinsky M, Lode A. Data on TOF-SIMS analysis of Cu(2+), Co(2+) and Cr(3+) doped calcium phosphate cements. Data Brief. 2017 Jun 13;13:353-355. doi: 10.1016/j.dib.2017.06.012. eCollection 2017 Aug.
    • von Rottkay E, Rackwitz L, Rudert M, Nöth U, Reichert JC. Function and activity after minimally invasive total hip arthroplasty compared to a healthy population. Int Orthop. 2017 Jul 12. doi: 10.1007/s00264-017-3541-z. [Epub ahead of print]
    • Fraissler L, Konrads C, Hoberg M, Rudert M, Walcher M. Treatment of hallux valgus deformity. EFORT Open Rev. 2016 Aug 25;1(8):295-302. doi: 10.1302/2058-5241.1.000005. eCollection 2016 Aug.
    • Mülek M, Seefried L, Genest F, Högger P. Distribution of Constituents andMetabolites of Maritime Pine Bark Extract (Pycnogenol(®)) into Serum, BloodCells, and Synovial Fluid of Patients with Severe Osteoarthritis: A RandomizedControlled Trial. Nutrients. 2017 Apr 28;9(5). pii: E443. doi: 10.3390/nu9050443.
    • Arnholdt J, Gilbert F, Blank M, Papazoglou J, Rudert M, Nöth U, Steinert AF.The Mayo conservative hip: complication analysis and management of the first 41cases performed at a University level 1 department. BMC Musculoskelet Disord.2017 Jun 9;18(1):250. doi: 10.1186/s12891-017-1613-2.
    • Boelch SP, Jordan MC, Arnholdt J, Rudert M, Luedemann M, Steinert AF. Loading with vancomycin does not decrease gentamicin elution in gentamicin premixed bone cement. J Mater Sci Mater Med. 2017 Jul;28(7):104. doi:10.1007/s10856-017-5915-6. Epub 2017 May 22.
    • Konrads C, Rueckl K, Barthel T, Walcher M, Rudert M, Plumhoff P. [Refixationof the biceps tendon onto the radial tuberosity using two suture anchors]. OperOrthop Traumatol. 2017 Aug;29(4):339-352. doi: 10.1007/s00064-017-0495-7. Epub2017 May 3. German. Erratum in: Oper Orthop Traumatol. 2017 May 23.
    • Armbruster N, Krieg J, Weißenberger M, Scheller C, Steinert AF. RescuedChondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge byFoamyviral Interleukin 1 Receptor Antagonist Gene Transfer. Front Pharmacol. 2017May 9;8:255. doi: 10.3389/fphar.2017.00255. eCollection 2017.
    • Kühn S, Lorenz RC, Weichenberger M, Becker M, Haesner M, O'Sullivan J,Steinert A, Steinhagen-Thiessen E, Brandhorst S, Bremer T, Gallinat J. Takingcontrol! Structural and behavioural plasticity in response to game-basedinhibition training in older adults. Neuroimage. 2017 May 17;156:199-206. doi:10.1016/j.neuroimage.2017.05.026.
    • Schamel M, Barralet JE, Groll J, Gbureck U. In vitro ion adsorption andcytocompatibility of dicalcium phosphate ceramics. Biomater Res. 2017 Jun8;21:10. doi: 10.1186/s40824-017-0096-4. eCollection
    • Schamel M, Groll J, Gbureck U. Simultaneous formation and mineralization ofstar-P(EO-stat-PO) hydrogels. Mater Sci Eng C Mater Biol Appl. 2017 Jun1;75:471-477. doi: 10.1016/j.msec.2017.02.088. Epub 2017 Feb 20.
    • Sancho A, Vandersmissen I, Craps S, Luttun A, Groll J. A new strategy tomeasure intercellular adhesion forces in mature cell-cell contacts. Sci Rep. 2017Apr 10;7:46152. doi: 10.1038/srep46152.
    • Lotz C, Schmid FF, Oechsle E, Monaghan MG, Walles H, Groeber-Becker F.Cross-linked Collagen Hydrogel Matrix Resisting Contraction To FacilitateFull-Thickness Skin Equivalents. ACS Appl Mater Interfaces. 2017 Jun 9. doi:10.1021/acsami.7b04017. [Epub ahead of print]
    • Jannasch M, Gaetzner S, Weigel T, Walles H, Schmitz T, Hansmann J. Acomparative multi-parametric in vitro model identifies the power of testconditions to predict the fibrotic tendency of a biomaterial. Sci Rep. 2017 May10;7(1):1689. doi: 10.1038/s41598-017-01584-9.
    • Christ B, Fey C, Cubukova A, Walles H, Dembski S, Metzger M. ScreeningApplications to Test Cellular Fitness in Transwell(®) Models After NanoparticleTreatment. Methods Mol Biol. 2017;1601:111-122. doi:10.1007/978-1-4939-6960-9_10.
    • Fahmy-Garcia S, van Driel M, Witte-Buoma J, Walles H, van Leeuwen JP, van OschG, Farrell E. Nell-1, HMGB1 and CCN2 enhance migration and vasculogenesis, butnot osteogenic differentiation compared to BMP2. Tissue Eng Part A. 2017 May 2.doi: 10.1089/ten.TEA.2016.0537. [Epub ahead of print]
    • Confalonieri D, La Marca M, van Dongen EMWM, Walles H, Ehlicke F. A NovelInjectable Recombinant Collagen I Peptide - based Macroporous Microcarrier AllowsSuperior Expansion of C2C12 and Human Bone Marrow - derived Mesenchymal StromalCells and Supports Deposition of Mineralized Matrix. Tissue Eng Part A. 2017 Mar 3. doi: 10.1089/ten.TEA.2016.0436. [Epub ahead of print]
    • Linz C, Collmann H, Kübler A, Böhm H, Schweitzer T. Patient-specificbiodegradable implant in pediatric craniofacial surgery. J Craniomaxillofac Surg.2017 Aug;45(8):1111. doi: 10.1016/j.jcms.2017.05.001. Epub 2017 May 11.
    • Seher A, Lagler C, Stühmer T, Müller-Richter UDA, Kübler AC, Sebald W, Müller TD, Nickel J. Utilizing BMP-2 muteins for treatment of multiple myeloma. PLoSOne. 2017 May 10;12(5):e0174884. doi: 10.1371/journal.pone.0174884. eCollection2017.
    • Jakubietz RG, Jakubietz MG, Meffert RH, Schmidt K. Multiple-level Replantationin Elderly Patients: Risk Versus Benefit. Plast Reconstr Surg Glob Open. 2017 Apr27;5(4):e1313. doi: 10.1097/GOX.0000000000001313. eCollection 2017 Apr.
    • Seefried L, Baumann J, Hemsley S, Hofmann C, Kunstmann E, Kiese B, Huang Y, Chivers S, Valentin MA, Borah B, Roubenoff R, Junker U, Jakob F. Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia. J Clin Invest. 2017 Apr 24. pii: 83731. doi: 10.1172/JCI83731. [Epub ahead of print]
    • Baumann B, Jungst T, Stichler S, Feineis S, Wiltschka O, Kuhlmann M, Lindén M, Groll J. Control of Nanoparticle Release Kinetics from 3D Printed Hydrogel Scaffolds. Angew Chem Int Ed Engl. 2017 Mar 22. doi: 10.1002/anie.201700153.[Epub ahead of print]
    • Appelt-Menzel A, Cubukova A, Günther K, Edenhofer F, Piontek J, Krause G, Stüber T, Walles H, Neuhaus W, Metzger M. Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells. Stem Cell Reports. 2017 Mar 22. pii: S2213-6711(17)30088-7. doi: 10.1016/j.stemcr.2017.02.021. [Epub ahead of print]
    • Glorieux FH, Devogelaer JP, Durigova M, Goemaere S, Hemsley S, Jakob F, Junker U, Ruckle J, Seefried L, Winkle PJ. BPS804 Anti-sclerostin Antibody in Adults with Moderate Osteogenesis Imperfecta: Results of a Randomized Phase 2a Trial. J  Bone Miner Res. 2017 Mar 29. doi: 10.1002/jbmr.3143. [Epub ahead of print]
    • Horas K, Fraissler L, Maier G, Jakob F, Seefried L, Konrads C, Rudert M, Walcher M. High Prevalence of Vitamin D Deficiency in Patients With Bone Marrow Edema Syndrome of the Foot and Ankle. Foot Ankle Int. 2017 Mar 1:1071100717697427. doi: 10.1177/1071100717697427. [Epub ahead of print]
    • Seefried L, Mueller-Deubert S, Krug M, Youssef A, Schuetze N, Ignatius A, Jakob F, Ebert R. Dissection of mechanoresponse elements in promoter sites of the mechanoresponsive CYR61 gene. Exp Cell Res. 2017 Mar 16. pii: S0014-4827(17)30152-0. doi: 10.1016/j.yexcr.2017.03.031. [Epub ahead of print]
    • Hecht N, Terveer N, Schollmayer C, Holzgrabe U, Meinel L. Opening NADPH oxidase inhibitors for in vivo translation. Eur J Pharm Biopharm. 2017 Mar 8. pii: S0939-6411(17)30192-3. doi: 10.1016/j.ejpb.2017.03.001. [Epub ahead of print]
    • Rueckl K, Konrads C, Barthel T, Rudert M, Boettner F, Plumhoff P. Arthroskopische Therapie bei spinoglenoidalem Ganglion. Z Orthop Unfall. 2017 Feb;155(1):100-103. doi: 10.1055/s-0043-100628. German.
    • Grabinger T, Bode KJ, Demgenski J, Seitz C, Delgado ME, Kostadinova F, Reinhold C, Etemadi N, Wilhelm S, Schweinlin M, Hänggi K, Knop J, Hauck C, Walles H, Silke J, Wajant H, Nachbur U, W Wei-Lynn W, Brunner T. Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells. Gastroenterology. 2017 Mar;152(4):867-879. doi: 10.1053/j.gastro.2016.11.019.
    • Pawelec KM, Confalonieri D, Ehlicke F, van Boxtel HA, Walles H, Kluijtmans SG. Osteogenesis and Mineralization of Mesenchymal Stem Cells in Collagen Type I Based Recombinant Peptide Scaffolds. J Biomed Mater Res A. 2017 Mar 1. doi: 10.1002/jbm.a.36049. [Epub ahead of print]
    • Moscaroli A, Jones G, Lühmann T, Meinel L, Wälti S, Blanc A, Fischer E, Hilbert M, Schibli R, Béhé M. Radiolabeled (111)In-FGF-2 Is Suitable for In Vitro/Ex Vivo Evaluations and In Vivo Imaging. Mol Pharm. 2017 Mar 6;14(3):639-648. doi: 10.1021/acs.molpharmaceut.6b00913.
    • Schwameis M, Kündig T, Huber G, von Bidder L, Meinel L, Weisser R, Aberer E, Härter G, Weinke T, Jelinek T, Fätkenheuer G, Wollina U, Burchard GD, Aschoff R, Nischik R, Sattler G, Popp G, Lotte W, Wiechert D, Eder G, Maus O, Staubach-Renz P, Gräfe A, Geigenberger V, Naudts I, Sebastian M, Reider N, Weber R, Heckmann M, Reisinger EC, Klein G, Wantzen J, Jilma B. Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial. Lancet Infect Dis. 2017 Mar;17(3):322-329. doi: 10.1016/S1473-3099(16)30529-1.
    • Blum C, Brückner T, Ewald A, Ignatius A, Gbureck U. Mg:Ca ratio as regulating factor for osteoclastic in vitro resorption of struvite biocements. Mater Sci Eng C Mater Biol Appl. 2017 Apr 1;73:111-119. doi: 10.1016/j.msec.2016.12.002.
    • Vindas Bolaños RA, Cokelaere SM, Estrada McDermott JM, Benders KE, Gbureck U, Plomp SG, Weinans H, Groll J, van Weeren PR, Malda J. The use of a cartilage decellularized matrix scaffold for the repair of osteochondral defects: the importance of long-term studies in a large animal model. Osteoarthritis Cartilage. 2017 Mar;25(3):413-420. doi: 10.1016/j.joca.2016.08.005.
    • Schamel M, Bernhardt A, Quade M, Würkner C, Gbureck U, Moseke C, Gelinsky M, Lode A. Cu(2+), Co(2+) and Cr(3+) doping of a calcium phosphate cement influences materials properties and response of human mesenchymal stromal cells. Mater Sci Eng C Mater Biol Appl. 2017 Apr 1;73:99-110. doi: 10.1016/j.msec.2016.12.052.
    • Schweinlin M, Rossi A, Lodes N, Lotz C, Hackenberg S, Steinke M, Walles H, Groeber F. Human barrier models for the in vitro assessment of drug delivery. Drug Deliv Transl Res. 2017 Apr;7(2):217-227. doi: 10.1007/s13346-016-0316-9.
    • Tabisz B, Schmitz W, Schmitz M, Luehmann T, Heusler E, Rybak JC, Meinel L, Fiebig JE, Mueller TD, Nickel J. Site-Directed Immobilization of BMP-2: Two Approaches for the Production of Innovative Osteoinductive Scaffolds. Biomacromolecules. 2017 Feb 17. doi: 10.1021/acs.biomac.6b01407. [Epub ahead of print]
    • Baldwin JG, Wagner F, Martine LC, Holzapfel BM, Theodoropoulos C, Bas O, Savi FM, Werner C, De-Juan-Pardo EM, Hutmacher DW. Periosteum tissue engineering in an orthotopic in vivo platform. Biomaterials. 2017 Mar;121:193-204. doi: 10.1016/j.biomaterials.2016.11.016.
    • Janikowska A, Matuszak J, Lyer S, Schreiber E, Unterweger H, Zaloga J, Groll J, Alexiou C, Cicha I. A novel human artery model to assess the magnetic accumulation of SPIONs under flow conditions. Sci Rep. 2017 Feb 8;7:42314. doi: 10.1038/srep42314.
    • Wistlich L, Rücker A, Schamel M, Kübler AC, Gbureck U, Groll J. A Bone Glue with Sustained Adhesion under Wet Conditions. Adv Healthc Mater. 2017 Feb;6(3). doi: 10.1002/adhm.201600902.
    • Schuerlein S, Schwarz T, Krziminski S, Gätzner S, Hoppensack A, Schwedhelm I, Schweinlin M, Walles H, Hansmann J. A versatile modular bioreactor platform for Tissue Engineering. Biotechnol J. 2017 Feb;12(2). doi: 10.1002/biot.201600326.
    • Wahl J, Furuishi T, Yonemochi E, Meinel L, Holzgrabe U. Characterization of complexes between phenethylamine enantiomers and β-cyclodextrin derivatives by capillary electrophoresis - determination of binding constants and complex mobilities. Electrophoresis. 2017 Jan 28. doi: 10.1002/elps.201600522. [Epub ahead of print]
    • Wahl J, Furuishi T, Quade M, Würkner C, Gbureck U, Moseke C, Gelinsky M, Lode A. Cu(2+), Co(2+) and Cr(3+) doping of a calcium phosphate cement influences materials properties and response of human mesenchymal stromal cells. Mater Sci Eng C Mater Biol Appl. 2017 Apr 1;73:99-110. doi: 10.1016/j.msec.2016.12.052.
    • Blum C, Brückner T, Ewald A, Ignatius A, Gbureck U. Mg:Ca ratio as regulating factor for osteoclastic in vitro resorption of struvite biocements. Mater Sci Eng C Mater Biol Appl. 2017 Apr 1;73:111-119. doi: 10.1016/j.msec.2016.12.002.
    • Schumacher M, Reither L, Thomas J, Kampschulte M, Gbureck U, Lode A, Gelinsky  M. Calcium phosphate bone cement/mesoporous bioactive glass composites for controlled growth factor delivery. Biomater Sci. 2017 Feb 3. doi: 10.1039/c6bm00903d. [Epub ahead of print]
    • Jakubietz MG, Mages L, Zahn RK, Kenn W, Jakubietz RG, Meffert RH. The role of CT scan in postoperative evaluation of distal radius fractures: Retrospective analysis in regard to complications and revision rates. J Orthop Sci. 2017 Jan 20. pii: S0949-2658(17)30001-5. doi: 10.1016/j.jos.2016.12.024. [Epub ahead of print]
    • Arnholdt J, Holzapfel BM, Sefrin L, Rudert M, Beckmann J, Steinert AF. [Individualized unicondylar knee replacement : Use of patient-specific implants and instruments]. Oper Orthop Traumatol. 2017 Feb;29(1):31-39. doi: 10.1007/s00064-017-0485-9. German.
    • Steinert AF, Beckmann J, Holzapfel BM, Rudert M, Arnholdt J. Bicompartmental individualized knee replacement : Use of patient-specific implants and instruments (iDuo™). Oper Orthop Traumatol. 2017 Feb;29(1):51-58. doi: 10.1007/s00064-017-0484-x.
    • Kremer A, Ribitsch I, Reboredo J, Dürr J, Egerbacher M, Jenner F, Walles H. 3D co-culture of meniscal cells and mesenchymal stem cells in collagen type I hydrogel on a small intestinal matrix - a pilot study towards equine meniscus tissue engineering. Tissue Eng Part A. 2017 Jan 18. doi: 10.1089/ten.TEA.2016.0317. [Epub ahead of print]
    • Stauch C, Ballweg T, Stracke W, Luxenhofer R, Mandel K. Burstable nanostructured micro-raspberries: Towards redispersible nanoparticles from dry powders. J Colloid Interface Sci. 2017 Mar 15;490:401-409. doi: 10.1016/j.jcis.2016.11.047.
    • Horas K, Arnholdt J, Steinert AF, Hoberg M, Rudert M, Holzapfel BM. Acetabular defect classification in times of 3D imaging and patient-specific treatment protocols. Orthopade. 2017 Jan 11. doi: 10.1007/s00132-016-3378-y. [Epub ahead of print]
    • Stichler S, Jungst T, Schamel M, Zilkowski I, Kuhlmann M, Böck T, Blunk T, Teßmar J, Groll J. Thiol-ene Clickable Poly(glycidol) Hydrogels for Biofabrication. Ann Biomed Eng. 2017 Jan;45(1):273-285. doi: 10.1007/s10439-016-1633-3.
    • Simann M, Le Blanc S, Schneider V, Zehe V, Lüdemann M, Schütze N, Jakob F, Schilling T. Canonical FGFs Prevent Osteogenic Lineage Commitment and Differentiation of Human Bone Marrow Stromal Cells Via ERK1/2 Signaling. J Cell Biochem. 2017 Feb;118(2):263-275. doi: 10.1002/jcb.25631.
    • Braun AC, Gutmann M, Ebert R, Jakob F, Gieseler H, Lühmann T, Meinel L. Matrix Metalloproteinase Responsive Delivery of Myostatin Inhibitors. Pharm Res. 2017 Jan;34(1):58-72. doi: 10.1007/s11095-016-2038-6.
    • Mentrup B, Girschick H, Jakob F, Hofmann C. A homozygous intronic branch-point deletion in the ALPL gene causes infantile hypophosphatasia. Bone. 2017 Jan;94:75-83. doi: 10.1016/j.bone.2016.10.022.
    Originalarbeiten 2016
    • Wandrey G, Wurzel J, Hoffmann K, Ladner T, Büchs J, Meinel L, Lühmann T. Probing unnatural amino acid integration into enhanced green fluorescent protein by genetic code expansion with a high-throughput screening platform. J Biol Eng. 2016 Sep 30;10:11.
    • Gilbert F, Böhm D, Eden L, Schmalzl J, Meffert RH, Köstler H, Weng AM, Ziegler D. Comparing the MRI-based Goutallier Classification to an experimental quantitative MR spectroscopic fat measurement of the supraspinatus muscle. BMC Musculoskelet Disord. 2016 Aug 22;17(1):355. doi: 10.1186/s12891-016-1216-3.
    • Kessler M, Esser E, Groll J, Tessmar J. Bilateral PLA/alginate membranes for the prevention of postsurgical adhesions. J Biomed Mater Res B Appl Biomater. 2016 Nov;104(8):1563-1570. doi: 10.1002/jbm.b.33503.
    • Kunz M, Wolf B, Schulze H, Atlan D, Walles T, Walles H, Dandekar T. Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools. Genes (Basel). 2016 Dec 26;8(1). pii: E8. doi: 10.3390/genes8010008. Review.
    • Konrads C, Rückl K, El Tabbakh M, Rudert M, Kircher S, Plumhoff P. Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae. SICOT J. 2016;2:41.
    • Heintel TM, Dannigkeit S, Fenwick A, Jordan MC, Jansen H, Gilbert F, Meffert R. How safe is minimally invasive pedicle screw placement for treatment of thoracolumbar spine fractures? Eur Spine J. 2016 Dec 8. [Epub ahead of print]
    • Wittmann K, Sieber C, von Stengel S, Kohl M, Freiberger E, Jakob F, Lell M, Engelke K, Kemmler W. Impact of whole body electromyostimulation on cardiometabolic risk factors in older women with sarcopenic obesity: the randomized controlled FORMOsA-sarcopenic obesity study. Clin Interv Aging. 2016 Nov 18;11:1697-1706.
    • Hoberg M, Holzapfel BM, Steinert AF, Kratzer F, Walcher M, Rudert M. [Treatment of acetabular bone defects in revision hip arthroplasty using the Revisio-System]. Orthopade. 2016 Dec 23. doi: 10.1007/s00132-016-3375-1. [Epub ahead of print] German.
    • Aeby M, Wyss T, Mentrup B, Kunstmann E, Jakob F, Aeberli D. Low-energy trauma-induced intercondylar femoral fracture. Clin Cases Miner Bone Metab. 2016 May-Aug;13(2):151-153.
    • Bode GH, Coué G, Freese C, Pickl KE, Sanchez-Purrà M, Albaiges B, Borrós S, van Winden EC, Tziveleka LA, Sideratou Z, Engbersen JF, Singh S, Albrecht K, Groll J, Möller M, Pötgens AJ, Schmitz C, Fröhlich E, Grandfils C, Sinner FM, James Kirkpatrick C, Steinbusch HW, Frank HG, Unger RE, Martinez-Martinez P. An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood-brain barrier uptake. Nanomedicine. 2016 Nov 21. pii: S1549-9634(16)30201-5. doi: 10.1016/j.nano.2016.11.009. [Epub ahead of print]
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    • Müller-Richter UD, Weyandt GH, Woeckel A, Kübler AC. Vermilion Reconstruction with Genital Mucosa. Plast Reconstr Surg Glob Open. 2016 May 5;4(5):e701. doi: 10.1097/GOX.0000000000000703.
    • Dotterweich J, Schlegelmilch K, Keller A, Geyer B, Schneider D, Zeck S, Tower RJ, Ebert R, Jakob F, Schütze N. Contact of myeloma cells induces a characteristic transcriptome signature in skeletal precursor cells -Implications for myeloma bone disease. Bone. 2016 Aug 9;93:155-166. doi: 10.1016/j.bone.2016.08.006.
    • Konrads C, Reppenhagen S, Belder D, Goebel S, Rudert M, Barthel T. Long-term outcome of anterior cruciate ligament tear without reconstruction: a longitudinal prospective study. Int Orthop. 2016 Oct 3.
    • Schwab A, Meeuwsen A, Ehlicke F, Hansmann J, Mulder L, Smits A, Walles H, Kock L. Ex vivo culture platform for assessment of cartilage repair treatment strategies. ALTEX. 2016 Oct 21. doi: 10.14573/altex.1607111.
    • Jannasch M, Weigel T, Engelhardt L, Wiezoreck J, Gaetzner S, Walles H, Schmitz T, Hansmann J. In vitro chemotaxis and tissue remodeling assays quantitatively characterize foreign body reaction. ALTEX. 2016 Oct 11. doi: 10.14573/altex.1610071.
    • Zazo H, Colino CI, Warzecha KT, Hoss M, Gbureck U, Trautwein C, Tacke F, Lanao JM, Bartneck M. Gold Nanocarriers for Macrophage-Targeted Therapy of Human Immunodeficiency Virus. Macromol Biosci. 2016 Oct 17. doi: 10.1002/mabi.201600359.
    • Fetsch C, Gaitzsch J, Messager L, Battaglia G, Luxenhofer R. Self-Assembly of Amphiphilic Block Copolypeptoids - Micelles, Worms and Polymersomes. Sci Rep. 2016 Sep 26;6:33491. doi: 10.1038/srep33491.
    • Hartmann S, Brisam M, Rauthe S, Driemel O, Brands RC, Rosenwald A, Kübler AC, Müller-Richter UD. Contrary melanoma-associated antigen-A expression at the tumor front and center: A comparative analysis of stage I and IV head and neck squamous cell carcinoma. Oncol Lett. 2016 Oct;12(4):2942-2947.
    • Fuchs A, Hartmann S, Ernestus K, Mutzbauer G, Linz C, Brands RC, Kübler AC, Müller-Richter UD. Mandibular intraosseous pseudocarcinomatous hyperplasia: a case report. J Med Case Rep. 2016 Sep 29;10(1):268.
    • Brands RC, Köhler O, Rauthe S, Hartmann S, Ebhardt H, Seher A, Linz C, Kübler AC, Müller-Richter UD. The prognostic value of GLUT-1 staining in the detection of malignant transformation in oral mucosa. Clin Oral Investig. 2016 Sep 8. [Epub ahead of print]
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    • Griesbeck S, Zhang Z, Gutmann M, Lühmann T, Edkins RM, Clermont G, Lazar AN, Haehnel M, Edkins K, Eichhorn A, Blanchard-Desce M, Meinel L, Marder TB. Water-Soluble Triarylborane Chromophores for One- and Two-Photon Excited Fluorescence Imaging of Mitochondria in Cells. Chemistry. 2016 Oct 4;22(41):14701-6. doi: 10.1002/chem.201602639. Epub 2016 Sep 15.
    • Castilho M, Rodrigues J, Vorndran E, Gbureck U, Quental C, Folgado J, Fernandes PR. Computational design and fabrication of a novel bioresorbable cage for tibial tuberosity advancement application. J Mech Behav Biomed Mater. 2017 Jan;65:344-355. doi: 10.1016/j.jmbbm.2016.08.036.
    • Aparicio JL, Rueda C, Manchón Á, Ewald A, Gbureck U, Alkhraisat MH, Jerez LB, Cabarcos EL. Effect of physicochemical properties of a cement based on silicocarnotite/calcium silicate on in vitro cell adhesion and in vivo cement degradation. Biomed Mater. 2016 Aug 2;11(4):045005. doi: 10.1088/1748-6041/11/4/045005.
    • Holzapfel BM, Wagner F, Martine LC, Reppenhagen S, Rudert M, Schuetz M, Denham J, Schantz JT, Hutmacher DW. Tissue engineering and regenerative medicine in musculoskeletal oncology. Cancer Metastasis Rev. 2016 Sep;35(3):475-87. doi: 10.1007/s10555-016-9635-z.
    • Lühmann T, Spieler V, Werner V, Ludwig MG, Fiebig J, Mueller TD, Meinel L. Interleukin-4-Clicked Surfaces Drive M2 Macrophage Polarization. Chembiochem. 2016 Nov 17;17(22):2123-2128. doi: 10.1002/cbic.201600480.
    • Schilling K, Amstalden MC, Meinel L, Holzgrabe U. Impurity profiling of l-asparagine monohydrate by ion pair chromatography applying low wavelength UV detection. J Pharm Biomed Anal. 2016 Nov 30;131:202-207. doi: 10.1016/j.jpba.2016.08.035.
    • Topuz F, Singh S, Albrecht K, Möller M, Groll J. DNA Nanogels To Snare Carcinogens: A Bioinspired Generic Approach with High Efficiency. Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12210-12213. doi: 10.1002/anie.201601983. Epub 2016 Sep 1.
    • Groeber F, Schober L, Schmid FF, Traube A, Kolbus-Hernandez S, Daton K, Hoffmann S, Petersohn D, Schäfer-Korting M, Walles H, Mewes KR. Catch-up validation study of an in vitro skin irritation test method based on an open source reconstructed epidermis (phase II). Toxicol In Vitro. 2016 Oct;36:254-61.  doi: 10.1016/j.tiv.2016.07.008. Epub 2016 Jul 17.
    • Lange J, Weil F, Riegler C, Groeber F, Rebhan S, Kurdyn S, Alb M, Kneitz H, Gelbrich G, Walles H, Mielke S. Interactions of donor sources and media influence the histo-morphological quality of full-thickness skin models. Biotechnol J. 2016 Oct;11(10):1352-1361. doi: 10.1002/biot.201600360.
    • Schweinlin M, Wilhelm S, Schwedhelm I, Hansmann J, Rietscher R, Jurowich C, Walles H, Metzger M. Development of an Advanced Primary Human In Vitro Model of the Small Intestine. Tissue Eng Part C Methods. 2016 Sep;22(9):873-883. Epub 2016 Aug 22.
    • Chintalapati C, Keller T, Mueller TD, Gorboulev V, Schäfer N, Zilkowski I, Veyhl-Wichmann M, Geiger D, Groll J, Koepsell H. Protein RS1 (RSC1A1) Downregulates the Exocytotic Pathway of Glucose Transporter SGLT1 at Low Intracellular Glucose via Inhibition of Ornithine Decarboxylase. Mol Pharmacol. 2016 Nov;90(5):508-521.
    • Gilbert F, Böhm D, Eden L, Schmalzl J, Meffert RH, Köstler H, Weng AM, Ziegler D. Comparing the MRI-based Goutallier Classification to an experimental quantitative MR spectroscopic fat measurement of the supraspinatus muscle. BMC Musculoskelet Disord. 2016 Aug 22;17(1):355. doi: 10.1186/s12891-016-1216-3.
    • Boelch SP, Jordan MC, Meffert RH, Jansen H. Comparison of open reduction and internal fixation and primary total hip replacement for osteoporotic acetabular fractures: a retrospective clinical study. Int Orthop. 2016 Aug 10. [Epub ahead of print]
    • Steiger C, Uchiyama K, Takagi T, Mizushima K, Higashimura Y, Gutmann M, Hermann C, Botov S, Schmalz HG, Naito Y, Meinel L. Prevention of colitis by controlled oral drug delivery of carbon monoxide. J Control Release. 2016 Oct 10;239:128-36. doi: 10.1016/j.jconrel.2016.08.030. Epub 2016 Aug 27. 
    • Maier GS, Kolbow K, Lazovic D, Horas K, Roth KE, Seeger JB, Maus U. Risk factors for pelvic insufficiency fractures and outcome after conservative therapy. Arch Gerontol Geriatr. 2016 Nov-Dec;67:80-5. doi: 10.1016/j.archger.2016.06.020. Epub 2016 Jul 15.
    • Maier GS, Maus U, Lazovic D, Horas K, Roth KE, Kurth AA. Is there an association between low serum 25-OH-D levels and the length of hospital stay in orthopaedic patients after arthroplasty? J Orthop Traumatol. 2016 Dec;17(4):297-302.
    • Horas K, Schnettler R, Maier G, Horas U. A novel intramedullary callus distraction system for the treatment of femoral bone defects. Strategies Trauma Limb Reconstr. 2016 Aug;11(2):113-21. doi: 10.1007/s11751-016-0255-5. Epub 2016 May 24.
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    • Wagner F, Holzapfel BM, Thibaudeau L, Straub M, Ling MT, Grifka J, Loessner D, Lévesque JP, Hutmacher DW. A Validated Preclinical Animal Model for Primary Bone Tumor Research. J Bone Joint Surg Am. 2016 Jun 1;98(11):916-25. doi: 10.2106/JBJS.15.00920.
    • Poh PS, Hutmacher DW, Holzapfel BM, Solanki AK, Woodruff MA. Data for accelerated degradation of calcium phosphate surface-coated polycaprolactone and polycaprolactone/bioactive glass composite scaffolds. Data Brief. 2016 Jan 22;7:923-6. doi: 10.1016/j.dib.2016.01.023. eCollection 2016 Jun.
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    • Holzapfel NP, Holzapfel BM, Theodoropoulos C, Kaemmerer E, Rausch T, Feldthusen J, Champ S, Clements JA, Hutmacher DW, Loessner D. Lycopene's Effects on Cancer Cell Functions within Monolayer and Spheroid Cultures. Nutr Cancer. 2016 Feb-Mar;68(2):350-63. doi: 10.1080/01635581.2016.1150498. Epub 2016 Mar 25.
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    • Kutscher M, Rosenberger M, Schmauss B, Meinel L, Lorenz U, Ohlsen K, Hellmann R, Germershaus O. Surface functionalization allowing repetitive use of optical sensors for real-time detection of antibody-bacteria interaction. J Biophotonics. 2016 Jul;9(7):730-7. doi: 10.1002/jbio.201500178. Epub 2015 Oct 21.
    • Kemmler W, Teschler M, Weissenfels A, Bebenek M, von Stengel S, Kohl M, Freiberger E, Goisser S, Jakob F, Sieber C, Engelke K. Whole-body electromyostimulation to fight sarcopenic obesity in community-dwelling older women at risk. Resultsof the randomized controlled FORMOsA-sarcopenic obesity study. Osteoporos Int. 2016 Nov;27(11):3261-3270.
    • Konrads C, Reppenhagen S, Plumhoff P, Rudert M, Steinert A, Barthel T. Nail-patella-syndrome in a young patient followed up over 10 years: relevance of the sagittal trochlear septum for patellofemoral pathology. SICOT J. 2016;2:26. doi: 10.1051/sicotj/2016017. Epub 2016 May 31.
    • Brunner U, Rückl K, Konrads C, Rudert M, Plumhoff P. Gorham-Stout syndrome of the shoulder. SICOT J. 2016;2:25. doi: 10.1051/sicotj/2016015. Epub 2016 May 16.
    • Jordan MC, Boelch S, Jansen H, Meffert RH, Hoelscher-Doht S. Does plastic suture deformation induce gapping after tendon repair? A biomechanical comparison of different suture materials. J Biomech. 2016 Sep 6;49(13):2607-2612. doi: 10.1016/j.jbiomech.2016.05.023.
    • Meininger M, Wolf-Brandstetter C, Zerweck J, Wenninger F, Gbureck U, Groll J, Moseke C. Electrochemically assisted deposition of strontium modified magnesium phosphate on titanium surfaces. Mater Sci Eng C Mater Biol Appl. 2016 Oct 1;67:65-71. doi: 10.1016/j.msec.2016.04.102. Epub 2016 May 4.
    • Rossi A, Wistlich L, Heffels KH, Walles H, Groll J. Isotropic Versus Bipolar Functionalized Biomimetic Artificial Basement Membranes and Their Evaluation in Long-Term Human Cell Co-Culture. Adv Healthc Mater. 2016 Aug;5(15):1939-48. doi: 10.1002/adhm.201600224. Epub 2016 Jun 10.
    • He Z, Wan X, Schulz A, Bludau H, Dobrovolskaia MA, Stern ST, Montgomery SA, Yuan H, Li Z, Alakhova D, Sokolsky M, Darr DB, Perou CM, Jordan R, Luxenhofer R, Kabanov AV. A high capacity polymeric micelle of paclitaxel: Implication of high dose drug therapy to safety and in vivo anti-cancer activity. Biomaterials. 2016 Sep;101:296-309. doi: 10.1016/j.biomaterials.2016.06.002. Epub 2016 Jun 4.
    • Nawroth JF, McDaniel JR, Chilkoti A, Jordan R, Luxenhofer R. Macromol. Biosci. 3/2016. Macromol Biosci. 2016 Mar;16(3):464. doi: 10.1002/mabi.201670014.
    • Wesselsky V, Kitz C, Jakob F, Eulert J, Raab P. Description and evaluation of operative deformity correction in calcium-deficiency rickets in Kaduna, northern Nigeria. Int Orthop. 2016 Apr;40(4):653-8. doi: 10.1007/s00264-015-2911-7. Epub 2015 Jul 30.
    • Dotterweich J, Tower RJ, Brandl A, Müller M, Hofbauer LC, Beilhack A, Ebert R, Glüer CC, Tiwari S, Schütze N, Jakob F. The KISS1 Receptor as an In Vivo Microenvironment Imaging Biomarker of Multiple Myeloma Bone Disease. PLoS One. 2016 May 9;11(5):e0155087. doi: 10.1371/journal.pone.0155087. eCollection 2016.
    • Reboredo JW, Weigel T, Steinert A, Rackwitz L, Rudert M, Walles H. Investigation of Migration and Differentiation of Human Mesenchymal Stem Cells on Five-Layered Collagenous Electrospun Scaffold Mimicking Native Cartilage Structure. Adv Healthc Mater. 2016 Sep;5(17):2191-8. doi: 10.1002/adhm.201600134. Epub 2016 May 17.
    • Wilken F, Banke IJ, Hauschild M, Winkler S, Schott K, Rudert M, Eisenhart-Rothe RV. [Endoprosthetic tumor replacement : Reconstruction of the extensor mechanism and complications]. Orthopade. 2016 May;45(5):439-45. doi: 10.1007/s00132-016-3255-8. German.
    • Groeber F, Engelhardt L, Lange J, Kurdyn S, Schmid FF, Rücker C, Mielke S, Walles H, Hansmann J. A first vascularized skin equivalent for as an alternative to animal experimentation. ALTEX. 2016;33(4):415-422. doi: 10.14573/altex.1604041.
    • Lotz C, Schmid FF, Rossi A, Kurdyn S, Kampik D, De Wever B, Walles H, Groeber FK. Alternative methods for the replacement of eye irritation testing. ALTEX. 2016;33(1):55-67. doi: 10.14573/altex.1508241. Epub 2015 Dec 2.
    • Ramachandran SD, Vivarès A, Klieber S, Hewitt NJ, Muenst B, Heinz S, Walles H, Braspenning J. Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies. Pharmacol Res Perspect. 2015 Oct;3(5):e00161. doi: 10.1002/prp2.161. Epub 2015 Aug 10.
    • Hartmann S, Neckel N, Seher A, Mutzbauer G, Brands RC, Linz C, Kübler AC, Müller-Richter UD. Erlotinib and gefitinib responsiveness in head and neck cancer cell lines-a comparing analysis with cetuximab. Clin Oral Investig. 2016 May;20(4):759-69. doi: 10.1007/s00784-015-1566-5. Epub 2015 Aug 23.
    • Moratin J, Hartmann S, Brands R, Brisam M, Mutzbauer G, Scholz C, Seher A, Müller-Richter U, Kübler AC, Linz C. Evaluation of miRNA-expression and clinical tumour parameters in oral squamous cell carcinoma (OSCC). J Craniomaxillofac Surg. 2016 Jul;44(7):876-81. doi: 10.1016/j.jcms.2016.04.017. Epub 2016 Apr 22.
    • Nietzer S, Baur F, Sieber S, Hansmann J, Schwarz T, Stoffer C, Häfner H, Gasser M, Waaga-Gasser AM, Walles H, Dandekar G. Mimicking Metastases Including Tumor Stroma: A New Technique to Generate a Three-Dimensional Colorectal Cancer Model Based on a Biological Decellularized Intestinal Scaffold. Tissue Eng Part C Methods. 2016 Jul;22(7):621-35. doi: 10.1089/ten.TEC.2015.0557. Epub 2016 Jun 3.
    • Gutmann M, Memmel E, Braun AC, Seibel J, Meinel L, Lühmann T. Biocompatible Azide-Alkyne "Click" Reactions for Surface Decoration of Glyco-Engineered Cells. Chembiochem. 2016 May 3;17(9):866-75. doi: 10.1002/cbic.201500582. Epub 2016 Mar 21.
    • Hiltensperger G, Hecht N, Kaiser M, Rybak JC, Hoerst A, Dannenbauer N, Müller-Buschbaum K, Bruhn H, Esch H, Lehmann L, Meinel L, Holzgrabe U. Quinolone Amides as Antitrypanosomal Lead Compounds with In Vivo Activity. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4442-52. doi: 10.1128/AAC.01757-15. Print 2016 Aug.
    • Göttlich C, Müller LC, Kunz M, Schmitt F, Walles H, Walles T, Dandekar T, Dandekar G, Nietzer SL. A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds. J Vis Exp. 2016 Apr 6;(110). doi: 10.3791/53885.
    • Brendtke R, Wiehl M, Groeber F, Schwarz T, Walles H, Hansmann J. Feasibility Study on a Microwave-Based Sensor for Measuring Hydration Level Using Human Skin Models. PLoS One. 2016 Apr 5;11(4):e0153145. doi: 10.1371/journal.pone.0153145 eCollection 2016.
    • Lühmann T, Mong SK, Simon MD, Meinel L, Pentelute BL. A perfluoroaromatic abiotic analog of H2 relaxin enabled by rapid flow-based peptide synthesis. Org Biomol Chem. 2016 Apr 7;14(13):3345-9. doi: 10.1039/c6ob00208k. Epub 2016 Mar 8.
    • Thiele OC, Kreppel M, Bittermann G, Bonitz L, Desmedt M, Dittes C, Dörre A, Dunsche A, Eckert AW, Ehrenfeld M, Fleiner B, Frerich B, Gaggl A, Gerressen M, Gmelin L, Hammacher A, Haßfeld S, Heiland M, Hemprich A, Hidding J, Hölzle F, Howaldt HP, Iizuka T, Kater W, Klein C, Klein M, Köhnke RH, Kolk A, Kübler AC, Kübler NR, Kunkel M, Kuttenberger JJ, Kreusch T, Landes C, Lehner B, Mischkowski RA, Mokros S, Neff A, Nkenke E, Palm F, Paulus GW, Piesold JU, Rasse M, Rodemer H, Rothamel D, Rustemeyer J, Sader R, Scheer M, Scheffler B, Schippers C, Schliephake H, Schmelzeisen R, Schramm A, Spitzer WJ, Stoll C, Terheyden H, Weingart D, Wiltfang J, Wolff KD, Ziegler CM, Zöller JE. Moving the mandible in orthognathic surgery - A multicenter analysis. J Craniomaxillofac Surg. 2016 May;44(5):579-83. doi: 10.1016/j.jcms.2016.01.024. Epub 2016 Feb 3.
    • Rosenbaum C, Schick MA, Wollborn J, Heider A, Scholz CJ, Cecil A, Niesler B, Hirrlinger J, Walles H, Metzger M. Activation of Myenteric Glia during Acute Inflammation In Vitro and In Vivo. PLoS One. 2016 Mar 10;11(3):e0151335. doi: 10.1371/journal.pone.0151335. eCollection 2016.
    • Diederichs S, Gabler J, Autenrieth J, Kynast KL, Merle C, Walles H, Utikal J, Richter W. Differential Regulation of SOX9 Protein During Chondrogenesis of Induced Pluripotent Stem Cells Versus Mesenchymal Stromal Cells: A Shortcoming for Cartilage Formation. Stem Cells Dev. 2016 Apr 15;25(8):598-609. Epub 2016 Mar 23.
    • Rudert M, Horas K, Hoberg M, Steinert A, Holzapfel DE, Hübner S, Holzapfel BM. The Wuerzburg procedure: the tensor fasciae latae perforator is a reliable anatomical landmark to clearly identify the Hueter interval when using the minimally-invasive direct anterior approach to the hip joint. BMC Musculoskelet Disord. 2016 Feb 3;17(1):57. doi: 10.1186/s12891-016-0908-z.
    • Merheb J, Temmerman A, Rasmusson L, Kübler A, Thor A, Quirynen M. Influence of Skeletal and Local Bone Density on Dental Implant Stability in Patients with Osteoporosis. Clin Implant Dent Relat Res. 2016 Apr;18(2):253-60. doi: 10.1111/cid.12290. Epub 2016 Feb 10.
    • Acqualagna L, Botrel L, Vidaurre C, Kübler A, Blankertz B. Large-Scale Assessment of a Fully Automatic Co-Adaptive Motor Imagery-Based Brain Computer Interface. PLoS One. 2016 Feb 18;11(2):e0148886. doi: 10.1371/journal.pone.0148886. eCollection 2016.
    • Meininger M, Schmitz T, Wagner T, Ewald A, Gbureck U, Groll J, Moseke C. Real-time measurement of protein adsorption on electrophoretically deposited hydroxyapatite coatings and magnetron sputtered metallic films using the surface acoustic wave technique. Mater Sci Eng C Mater Biol Appl. 2016 Apr 1;61:351-4. doi: 10.1016/j.msec.2015.12.075. Epub 2015 Dec 30.
    • Brisam M, Rauthe S, Hartmann S, Linz C, Brands RC, Kübler AC, Rosenwald A, Müller-Richter UD. Expression of MAGE-A1-A12 subgroups in the invasive tumor front and tumor center in oral squamous cell carcinoma. Oncol Rep. 2016 Apr;35(4):1979-86. doi: 10.3892/or.2016.4600. Epub 2016 Jan 28.
    • Whyte MP, Rockman-Greenberg C, Ozono K, Riese R, Moseley S, Melian A, Thompson DD, Bishop N, Hofmann C. Asfotase Alfa Treatment Improves Survival for Perinatal and Infantile Hypophosphatasia. J Clin Endocrinol Metab. 2016 Jan;101(1):334-42. doi: 10.1210/jc.2015-3462. Epub 2015 Nov 3.
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    Originalarbeiten 2013
    • Koerdt S, Siebers J, Bloch W, Ristow O, Kuebler AC, Reuther T. Immunohistochemial study on the expression of von Willebrand factor (vWF) after onlay autogenous iliac grafts for lateral alveolar ridge augmentation. Head Face Med. 2013 Dec 11;9:40. doi: 10.1186/1746-160X-9-40.
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    • Wannhoff A, Bölck B, Kübler AC, Bloch W, Reuther T. Oxidative and nitrosative stress and apoptosis in oral mucosa cells after ex vivo exposure to lead and benzo[a]pyrene. Toxicol In Vitro. 2013 Mar;27(2):915-21
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    Originalarbeiten 2012
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    • Bittner T, Lorbeer N, Reuther T, Böhm H, Kübler AC, Müller-Richter UD. Hemimandibulectomy after bisphosphonate treatment for complex regional pain syndrome: A case report and review on the prevention and treatment of bisphosphonate-related osteonecrosis of the jaw. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jan;113(1):41-7. Epub 2011 Mar 31.
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    Originalarbeiten 2010
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    Originalarbeiten 2009
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    • Steinert AF, Proffen B, Kunz M, Hendrich C, Ghivizzani SC, Nöth U, Rethwilm A, Eulert J, Evans CH. Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. Arthritis Res Ther. 2009;11(5):R148. Epub 2009 Oct 2.
    • Ebert R, Zeck S, Krug R, Meissner-Weigl J, Schneider D, Seefried L, Eulert J, Jakob F. Pulse treatment with zoledronic acid causes sustained commitment of bone marrow derived mesenchymal stem cells for osteogenic differentiation. Bone. 2009 May;44(5):858-64. Epub 2009 Jan 23.
    • Langdahl BL, Rajzbaum G, Jakob F, Karras D, Ljunggren O, Lems WF, Fahrleitner-Pammer A, Walsh JB, Barker C, Kutahov A, Marin F. Reduction in fracture rate and back pain and increased quality of life in postmenopausal women treated with teriparatide: 18-month data from the European Forsteo Observational Study (EFOS). Calcif Tissue Int. 2009 Dec;85(6):484-93. Epub 2009 Oct 13.
    • Rachner TD, Singh SK, Schoppet M, Benad P, Bornhäuser M, Ellenrieder V, Ebert R, Jakob F, Hofbauer LC. Zoledronic acid induces apoptosis and changes the TRAIL/OPG ratio in breast cancer cells. Cancer Lett. 2010 Jan 1;287(1):109-16. Epub 2009 Jul 3.
    • Lienau J, Schmidt-Bleek K, Peters A, Haschke F, Duda GN, Perka C, Bail HJ, Schütze N, Jakob F, Schell H. Differential regulation of blood vessel formation between standard and delayed bone healing. J Orthop Res. 2009 Sep;27(9):1133-40.
    • Goebel S, Lienau J, Rammoser U, Seefried L, Wintgens KF, Seufert J, Duda G, Jakob F, Ebert R. FGF23 is a putative marker for bone healing and regeneration. J Orthop Res. 2009 Sep;27(9):1141-6.
    • Klammert U, Nickel J, Würzler K, Klingelhöffer C, Sebald W, Kübler AC, Reuther T. Biological activity of a genetically modified BMP-2 variant with inhibitory activity. Head Face Med. 2009 Feb 2;5:6.
    • Klammert U, Böhm H, Schweitzer T, Würzler K, Gbureck U, Reuther J, Kübler A. Multi-directional Le Fort III midfacial distraction using an individual prefabricated device. J Craniomaxillofac Surg. 2009 Jun;37(4):210-5. Epub 2009 Jan 21.
    • Eastell R, Black DM, Boonen S, Adami S, Felsenberg D, Lippuner K, Cummings SR, Delmas PD, Palermo L, Mesenbrink P, Cauley JA; HORIZON Pivotal Fracture Trial. Effect of once-yearly zoledronic acid five milligrams on fracture risk and change in femoral neck bone mineral density. J Clin Endocrinol Metab. 2009 Sep;94(9):3215-25. Epub 2009 Jun 30. (F. Jakob as an investigator)
    • Morbach H, Dick A, Beck C, Stenzel M, Müller-Hermelink HK, Raab P, Girschick HJ. Association of chronic non-bacterial osteomyelitis with Crohn's disease but not with CARD15 gene variants. Rheumatol Int. 2010 Mar;30(5):617-21. Epub 2009 Jul 5.
    • Ettl V, Wollmerstedt N, Kirschner S, Morrison R, Pasold E, Raab P. Calcaneal lengthening for planovalgus deformity in children with cerebral palsy. Foot Ankle Int. 2009 May;30(5):398-404.
    • Weiser B, Sommer F, Neubauer M, Seitz A, Tessmar J, Goepferich A, Blunk T. Ascorbic acid enhances adipogenesis of bone marrow-derived mesenchymal stromal cells. Cells Tissues Organs. 2009;189(6):373-81. Epub 2008 Sep 4.
    • Sommer F, Brandl F, Weiser B, Tesmar J, Blunk T, Göpferich A. FACS as useful tool to study distinct hyalocyte populations. Exp Eye Res. 2009 May;88(5):995-9. Epub 2008 Dec 6.
    • Ebert R, Zeck S, Krug R, Meissner-Weigl J, Schneider D, Seefried L, Eulert J, Jakob F. Pulse treatment with zoledronic acid causes sustained commitment of bone marrow derived mesenchymal stem cells for osteogenic differentiation. Bone. 2009 May;44(5):858-64. Epub 2009 Jan 23.
    • Goebel S, Lienau J, Rammoser U, Seefried L, Wintgens KF, Seufert J, Duda G, Jakob F, Ebert R. FGF23 is a putative marker for bone healing and regeneration. J Orthop Res. 2009 Sep;27(9):1141-6.
    • Tamimi F, Torres J, Gbureck U, Lopez-Cabarcos E, Bassett DC, Alkhraisat MH, Barralet JE. Craniofacial vertical bone augmentation: a comparison between 3D printed monolithic monetite blocks and autologous onlay grafts in the rabbit. Biomaterials. 2009 Oct;30(31):6318-26. Epub 2009 Aug 19.
    • Barralet J, Gbureck U, Habibovic P, Vorndran E, Gerard C, Doillon CJ. Angiogenesis in calcium phosphate scaffolds by inorganic copper ion release. Tissue Eng Part A. 2009 Jul;15(7):1601-9.
    • Alkhraisat MH, Rueda C, Jerez LB, Tamimi Mariño F, Torres J, Gbureck U, Lopez Cabarcos E. Effect of silica gel on the cohesion, properties and biological performance of brushite cement. Acta Biomater. 2010 Jan;6(1):257-65. Epub 2009 Jun 10.
    • Kotzsch A, Nickel J, Seher A, Sebald W, Müller TD. Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity. EMBO J. 2009 Apr 8;28(7):937-47. Epub 2009 Feb 19.
    • Heinecke K, Seher A, Schmitz W, Mueller TD, Sebald W, Nickel J. Receptor oligomerization and beyond: a case study in bone morphogenetic proteins. BMC Biol. 2009 Sep 7;7:59.
    • Kotzsch A, Nickel J, Sebald W, Mueller TD. Purification, crystallization and preliminary data analysis of ligand-receptor complexes of growth and differentiation factor 5 (GDF5) and BMP receptor IB (BRIB). Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Aug 1;65(Pt 8):779-83. Epub 2009 Jul 25.
    • Steinert AF, Proffen B, Kunz M, Hendrich C, Ghivizzani SC, Nöth U, Rethwilm A, Eulert J, Evans CH. Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. Arthritis Res Ther. 2009;11(5):R148. Epub 2009 Oct 2.
    • Heymer A, Bradica G, Eulert J, Nöth U. Multiphasic collagen fibre-PLA composites seeded with human mesenchymal stem cells for osteochondral defect repair: an in vitro study. J Tissue Eng Regen Med. 2009 Jul;3(5):389-97.
    • Wollmerstedt N, Nöth U, Ince A, Ackermann H, Martell JM, Hendrich C. The Daily Activity Questionnaire: a novel questionnaire to assess patient activity after total hip arthroplasty. J Arthroplasty. 2010 Apr;25(3):475-480.e1-3. Epub 2009 Feb 20.
    • Klammert U, Reuther T, Blank M, Reske I, Barralet JE, Grover LM, Kübler AC, Gbureck U. Phase composition, mechanical performance and in vitro biocompatibility of hydraulic setting calcium magnesium phosphate cement. Acta Biomater. 2010 Apr;6(4):1529-35. Epub 2009 Nov 1.
    • Meyer-Marcotty P, Reuther T, Stellzig-Eisenhauer A. Bridging of the sella turcica in skeletal Class III subjects. Eur J Orthod. 2010 Apr;32(2):148-53. Epub 2009 Sep 13.
    • Lienau J, Schmidt-Bleek K, Peters A, Haschke F, Duda GN, Perka C, Bail HJ, Schütze N, Jakob F, Schell H. Differential regulation of blood vessel formation between standard and delayed bone healing. J Orthop Res. 2009 Sep;27(9):1133-40.
    • Steinert AF, Palmer GD, Pilapil C, Nöth U, Evans CH, Ghivizzani SC. Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Tissue Eng Part A. 2009 May;15(5):1127-39.
    • Goebel S, Steinert AF, Barthel T. Surgical management of a double-layered patella: a case report. Arch Orthop Trauma Surg. 2009 Aug;129(8):1071-5. Epub2008 Aug 2.
    • Djouad F, Rackwitz L, Song Y, Janjanin S, Tuan RS. ERK1/2 activation induced by inflammatory cytokines compromises effective host tissue integration of engineered cartilage. Tissue Eng Part A. 2009 Oct;15(10):2825-35.
    • Jakubietz RG, Jakubietz MG, Jakubietz DF, Koehler G, Zeplin PH, Meffert RH, Schmidt K. Ischial pressure sores: reconstruction using the perforator-basedreverse flow musculocutaneous 180 degrees propeller flap. Microsurgery.2009;29(8):672-5
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